About MitraClip™ Therapy

Learn about a safe, proven way to fix your leaky mitral valve.

MitraClip Therapy Overview

Understanding MitraClip Therapy

Fixing your mitral valve leak without open-heart surgery

MitraClip Therapy is a minimally invasive procedure that repairs your mitral valve. During the procedure, the doctor guides a thin tube (called a catheter) through a vein in your groin to reach your heart. A small clip, about the size of a dime, is attached to the leaflets of your mitral valve to help it close more completely and restore normal blood flow.

The MitraClip Therapy procedure typically takes 1 to 3 hours1 and allows for a shorter recovery time than open-heart surgery. Most people return home after one day in the hospital and often feel improvement soon after, resuming most day-to-day activities after 2 weeks.1

Results

MitraClip Therapy is proven safe and effective

With more than 20 years of proven outcomes and experience in over 250,000 people worldwide, MitraClip Therapy
has been shown to safely and effectively reduce mitral regurgitation, improve survival, reduce hospitalizations, and help patients feel better.2

In a large clinical study:

47% fewer heart failure hospitalizations after 5 years compared to medication alone

47%

fewer heart failure hospitalizations
after 5 years compared to medication alone2

28% lower risk of death than those treated with medication alone

28%

lower risk of death than those treated with medication alone2

99% of people were free from device-related compications at 5 years

99%

of people were free from device-related complications at 5 years2

2x more likkely to see major improvements in quality of life

2x

more likely to see major improvements in quality of life compared to medication alone3

Is MitraClip Therapy right for me?

Use our quick questionnaire to see if you might be a candidate for MitraClip Therapy.

Start Questionnaire

Start an assessment

Ready to discuss with your doctor?

If your mitral regurgitation symptoms are interrupting your daily life, download this discussion guide to prepare for your next doctor’s appointment.

Download Discussion Guide

Find a MitraClip Therapy cardiologist near me

Find a cardiologist near me

Meet with a specialized care team experienced with the MitraClip Therapy procedure.
Important Safety Information
Important Safety Information

What is MitraClip™ Therapy approved for?

Available by prescription only.

MitraClip therapy is a minimally invasive procedure approved for treating patients with clinically significant mitral regurgitation due to either (a) a deteriorated mitral valve in patients who are deemed to be at prohibitive risk for surgery, or (b) mitral valve in patients who have heart failure and reduced pumping function who remain symptomatic despite maximally tolerated medications to treat their heart failure.

Patients should work with their doctor and a multidisciplinary heart team, which may include a heart surgeon and cardiologist with experience treating heart failure, to confirm their surgical risk and to ensure that they are on the optimal medications. The heart team will determine if transcatheter edge-to-edge valve repair is clinically appropriate, and if the patient meets the indications for the MitraClip procedure.

Who should not have the MitraClip Procedure?

Patients that have any of the following conditions may not be good candidates for the MitraClip Procedure: Patients with intolerance or allergy to procedural anticoagulation, untreatable hypersensitivity to implant components (nickel-titanium alloy, cobalt-chromium alloy), or active endocarditis or other active infection of the mitral valve.

What are the possible complications associated with the MitraClip Procedure?

As with any medical procedure, there is a possibility of complications. The most serious complications of the MitraClip procedure includes, but are not limited to: death, stroke (a condition in which decreased blood flow to the brain can result in brain damage and may cause severe disability), transient ischemic attack (stroke symptoms that last only a few minutes), major vascular complications (damage to a major blood vessel that may require emergency surgery or urgent cardiac surgery), life threatening bleeding event (a major bleeding event that requires a blood transfusion).  For additional potential risks and complications, please consult with your physician or heart team.

Talk to your doctor to learn more about the risks associated with MitraClip Therapy and ask for the detailed Important Safety Information if you'd like to review the full list of complications.

References:

  1. Kar S et al. Contemporary outcomes following transcatheter edge-to-edge repair: 1-year results from the EXPAND study. JACC Cardiovasc Interv. 2023;16(5):589–602.
  2. Stone GW et al. Five-year follow-up after transcatheter repair of secondary mitral regurgitation. N Engl J Med. 2023;388(22):2037-2048.
  3. Arnold SV et al. Health status after transcatheter mitral-valve repair in heart failure and secondary mitral regurgitation: COAPT trial. J Am Coll Cardiol. 2019;73(17):2123-2132.

Data on file at Abbott.

MAT-2600337 v1.0 | Item approved for U.S. use only